How to take
You should not use Endocet if you have recently used alcohol, sedatives, tranquilizers, or other opioid medications.
Ooxycodone can slow or stop your breathing, and may be habit-forming. Use only your prescribed dose, and swallow the pill whole to avoid a potentially fatal dose. Never share Endocet with another person.
MISUSE OF THIS MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).
Oxycodone may cause life-threatening withdrawal symptoms in a newborn if the mother has taken Endocet during pregnancy.
An overdose of acetaminophen can damage your liver or cause death. Call your doctor at once if you have nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).
Stop taking this medicine and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
How effective is Endocet?
You should not use Endocet if you are allergic to acetaminophen (Tylenol) or oxycodone, or if:
- you have severe asthma or breathing problems;
- you have a blockage in your stomach or intestines, including paralytic ileus; or
- you have recently used alcohol, sedatives, tranquilizers, or other opioid medications.
Some medicines can interact with oxycodone and cause a serious condition called serotonin syndrome. Be sure your doctor knows if you also take medicine for depression, mental illness, Parkinson’s disease, migraine headaches, serious infections, or prevention of nausea and vomiting. Ask your doctor before making any changes in how or when you take your medications.
To make sure Endocet is safe for you, tell your doctor if you have:
- breathing problems, sleep apnea;
- liver disease, cirrhosis, or if you drink alcohol daily;
- a history of drug abuse, alcohol addiction, or mental illness;
- kidney disease, urination problems;
- problems with your gallbladder, pancreas, thyroid, or adrenal gland;
- a history of head injury, brain tumor, or seizures; or
- if you use a sedative like Valium (diazepam, alprazolam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Versed, Xanax, and others).
Endocet is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
If you use oxycodone while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. You should not breastfeed while using this medicine.
Acetaminophen and oxycodone may pass into breast milk and could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Side Effects
What are the side effects of Endocet?
Get emergency medical help if you have signs of an allergic reaction to Endocet: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, acetaminophen may cause a severe skin reaction that can be fatal. This could occur even if you have taken acetaminophen in the past and had no reaction. Stop taking Endocet and call your doctor right away if you have skin redness or a rash that spreads and causes blistering and peeling.
Oxycodone can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Call your doctor at once if you have:
- noisy breathing, sighing, shallow breathing, breathing that stops during sleep;
- a light-headed feeling, like you might pass out;
- confusion, unusual thoughts or behavior;
- seizure (convulsions);
- problems with urination;
- infertility, missed menstrual periods;
- impotence, sexual problems, loss of interest in sex;
- liver problems – nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness; or
- high levels of serotonin in the body – agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea.
Serious breathing problems may be more likely in older adults and in those who are debilitated or have wasting syndrome or chronic breathing disorders.
Common Endocet side effects include:
- headache, drowsiness, tiredness;
- nausea, vomiting, stomach pain, constipation;
- blurred vision; or
- dry mouth.
This is not a complete list of side effects and others may occur.
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